How low to tune largely depends on (a) the instrument you're playing, and where it comes alive, (b) the gauge of strings you're using and (c) where you want it. I play an Apollonio, and you won't find a better make of 12 in the world - especially for the prices Nick charges. For years I kept mine tuned three frets down, and then one day after restraining accidentally tuned it four frets down. It was excellent before, but - WOW. That's where it wants to be. It resonates like nobody's business. Other instruments sound better in other tunings. For what it's worth, many people tune at least two frets down. But mind the string gauges! Too light and they'll be slack, which gives you bad intonation. Too heavy and they'll be hard to play, and stress the instrument. As for a make of strings, I like D'addario's. Of course, since I keep mine tuned so low I make up my own custom sets from singles. Hope this helps! Good luck, and seriously look at Apollonios. Unbelievable sound, quality, and playability. Dan
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