I just found another program which will read text aloud. It has a couple of features that ReadPlease does not. It can be set to automatically read anything in the clipboard, and it has a feature to 'teach' it new pronunciation/vocabulary. It will even read entire web pages, by connecting via URL...

It, again, is not a complete solution, as it does not totally solve the problem for a person of limited vision of navigating to and highlighting exactly what they want to read....but it will do lots of tricks which MAY be useful.

take a look