Muscadines are the naturally occuring wild grapes of the Southeastern U.S. We have thousands of wild Muscadine vines on our property. When European settlers couldn't get the wine and table grape varieties they were familiar with to grow in the south's humid environment, they began experimenting with selectively breeding the native Muscadines. Scuppernongs are a named variety of Muscadine and are, by far, the most common and popular variety. Scuppernongs are about ten times the size of their wild native forbears and much tastier.

BTW, wild Muscadines are sometimes known as "Fox Grapes" (from Aesop's fable about the fox and the sour grapes) because their vines climb into trees and many of the grapes are well out of reach.

BTW again, over the years, varieties of European grapes that will tolerate high humidity have been developed. There is an active winery about an hour east of where I live in the Florida Panhandle and they make several varieties.