In addition to all the good advice already given above:

Depending on the material you have to choose from, you can try to take the audience through musical "images" or "stories". Grouping songs according to some link/thread. For example "childhood", "parenthood", "war", "poverty", "love", etc. But in this case avoid two songs that take the same view of the subject; change the angle of perspective.

I use both 6- and 12-string guitars in my performances (20/80 respectively). I therefore also have to avoid constant guitar changes, constant tuning changes etc

Most important, I think: "play" with the mood. Not simply fast-moderate-slow, but also "funny", "sad", "angry" etc. Goes back to telling a story, as I described above, and is best combined with that.