A few BTWs:

Jerry Garcia was missing his right middle finger at the 1st joint which mainly affected the way he held his pick. I read somewhere that he was really adept at shifting between strumming and finger-picking mid-song since he could slip the pick away between his index finger and the stump.

The guy who plays (played) guitar for Black Sabbath lost the tips of 3 fingers on his left hand. He played through his whole career with prosthetic finger tips (!)