I guess being 'nebby' as used by African Americans in Pittsburgh area does mean sticking your nose in other people's business.

As to 'conk', Clarence Major's dictionary on Black American slang "Juba to Jive" has this entry for 'conk':
"{n} 1930-1950s; pomade for the hair; a hairstyle; the human head itself; brains or intelligence. in general white use during the same time period, this term refered mostly to the human head or the face or nose, and to the act of hitting someone on the head."

Majors also has an entry for 'conk-buster', 'conk-busting': [n;adj],{19302-1950s} anything proving mentally difficult, also sometimes referred to what drugs or liquor did to the mind; from the forties into the fifites, cheap whiskey or wine. Example: "That cat comes up with some conk-busting questions."

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Well the brand name "Conkalene" had to come from some where..I guess it fits with the 'conk' having to do with the head.