And the winner is: "Singles" 1992
http://www.imdb.com/title/tt0105415/
Bridget Fonda, Kyra Sedgewick, Matt Dillon, Bill Pullman, Eric Stoltz, Tom Skerritt. Directed by Cameron Crowe
I found it by googleing "Film SET in Seattle" rather than "films shot in Seattle.
Thanks for the help.