I don't see why it can't be possible to have a web-page which can accomodate the visually impaired yet be useful for other browsers too.

Max, here are a few other links which could be of use.

Designing Web Pages for Blind Readers
Resource Guide for the Visually Impaired
Blindness Related Resources
Designing Accessible Web Pages
recommendation on customized web pages for blind users
text matters - web pages for the visually impaired

Enjoy!