Rick. Glucosomine works. Simple as that. Hard part is doing a good trial. You've @#$%ing got to take it three times a day (500 mg) for a total of 1500 mg for six weeks to see results. Improved my knees so much I forget I ever had a problem. Take it. let me know how it turns out. I have read the many studies at the US National Library of Medicine NIH. But be impeccable. don't miss a single dose, ok?best wishes, chance