Strong strains of weed do screw with your brain quite badly - my usually low-key partner became convinced government helicopters were following him wherever he went. I tried to tell him at the time that he wasn't important enough and it was paranoia induced by the weed (not Skunk incidentally but 'White Widow' - one of stronger strains of weed out there with a THC content of 20-25%) but he persisted freaking out about black helicopters until his regular access ceased to be so easy and he consequently ceased smoking. Needless to say, I'm glad he hasn't smoked much since then.

Otherwise, most of the people I've known have regularly smoked resin over the years. A much milder brew which so far as I know anecdotally is not reputed to induce the kinds of extreme paranoia and psychosis that extremely strong strains of weed more likely to do.