I don't know about the ancient lyres but modern ones are well and thriving at places like Rudolf Steiner schools and Anthroposophical communities. Where I worked, at Hohepa Homes here in NZ, there are several people who play in groups and they sound beautiful, especially with the harmonies. The Hohepa players aren't on video but here's an example I found with the type of lyre they play.
The tuning is chromatic, with the 'white notes' on the right side, played with the right hand and the 'black notes' on the left, played by the left hand.
There are also smaller, solid body lyres, called Bordon Lyres (or something like that - I don't know how they spell it and I can't find it on-line) which are tuned to a chord. You need 2 or 3 set up so you just gently strum the one with the chord you need. They sound beautiful, especially when tuned to minor or modal chords - a gentle accompaniment to songs.
I didn't learn the lyre because the technique is different - not plucked like guitar or harp but the finger tips are placed on the strings, then pulled away so the string sounds. It's tricky to explain.
Robyn