In my day job as a senior manager in a university library, I read hundreds and hundreds of job applications - some with resumes and some without - for over 30 years. We generally used formal application forms but, in latter years, allowed resumes. For some jobs we had between thirty and a hundred applications.

What did I look for?

Literate writing - accurate and to the point - free of jargon.
If handwritten - legible and free of crossings out.
Historical clarity - a concise, readable summary of past education and experience, relevant or not.
Most important - a clear and honest statement of why the applicant wanted our particular job and what skill they believed they could genuinely bring to it.

What put me off an application?

Meaningless phrases such as "I am a people person".
Obvious bullshit and waffle (you learn to pick it out).
A general resume which appeared to have no relationship to the job on offer.
People who were highly educated but believed that their qualifications alone entitled them to the job.

From those 30-100 applications we interviewed 6-8 people at most.