So Sodium fluoride is used in toothpaste...true, but have you ever read the Hazcard for it? Maybe you should before declaring it safe.

The lethal dose for a 70 kg (154 lb) human is estimated at 5–10 g.[7] Sodium fluoride is classed as toxic by both inhalation (of dusts or aerosols) and ingestion.[13] In high enough doses, it has been shown to affect the heart and circulatory system.