The Mudcat Café TM
Thread #154975   Message #3648971
Posted By: Q (Frank Staplin)
07-Aug-14 - 12:47 AM
Thread Name: BS: Anybody else watching Ebola break out?
Subject: RE: BS: Anybody else watching Ebola break out?
Vaccine testing is at least a year away.

A vaccine that works for Americans and/or Europeans is at least a year away.
The vaccine likely would be useless in Africa because Africans have different antibodies in their systems (Director, Wistar Institute Vaccine Center). Antibodies influence how a body receives the vaccine.

NIAID director Anthony Fauci says there are 3-4 vaccine candidates in preclinical trials. The FDA may approve the first one for testing in September, but is will be the end of 2015 before testing is ended.

The vaccine itself is a virus, engineered to lack the gene necessary for replication. It is equipped with two Ebola genes that, once the vaccine enters the body's cells, will cause the body's immune system to produce antibodies.
The work is being done on non-human primates.

There also is continuing work with a drug treatment, developed by Mapp Biopharmaceutical of San Diego (ZMapp) financed by the Defense Threat Reduction Agency.

"Why the Ebola Vaccine Won't Be Administered in Africa," Joe Kloc, Newsweek, 8/6/14

Note- Dr. Kent Brantly, now being treated at Emory Hospitals in Atlanta, not only received the ZMapp serum, but previously received blood from a survivor, according to Samaritan's Purse President Franklin Graham. Samaritan's Purse is working with the Emory unit.
The idea was that the blood contained antibodies that would help the infected person.