> nature is the whole of the case

Well, yes, but the human mind is part of nature, and if that mind everywhere on earth has demonstrated the need to believe in a meaning-imparting deity or deities to keep it from emotional disorganization and collapse, complaining about it seems to be extraordinarily small-minded.

The most significant argument is not with theism but with the negative - and often dangerous - effects of certain beliefs and practices. (Or with deism, for that matter, which at least requires fewer imaginative assumptions.)