Very few people over here know anyone who has been shot. There's a good reason for that.

Not sure what Goofus is asking or why? Certainly as we get an aging population, incidence of oncomortality increases. The biological process is the biological process, I fail to see his point.

Certainly, homeostasis as a concept allows healthy bodies to regulate internal pH values and that is important. An increase in pH may be hostile to viral clusters (antiretrovirals encourage this) but has side effects where naturally occurring acidic antibodies need to thrive. DNA itself has a value less than pH7.

A non oncological example of homeostatic failure that is rather common would be diabetes.