I played the blues Four until late on an English Concertina on my lp "playing for time".
I also recorded "sitting on top of the world£ on duet concertina, and fogyism and backwater blues on the concertina compilation boxing clever which is still available from my website www.dickmiles.com. the advantage of duet concertina for blues is that it can use piano blues techniquesfor a model.
the problem with concertina and blues is the inabilty to bend notes,the piano has the same problem, but certain piano techniques overcome that problem.
vibrato can be imitated by shaking bellows, or tapping on knee whilst sitting, glissandos IMO cannot because you are stuck with strict senitones.