I can't help with chords or tunings, but I can do lyrics, and it seems these have never been posted at Mudcat before, so we might as well have them here. My transcription from Spotify:


BOUND TO LOSE
"Traditional"
As recorded by Holy Modal Rounders on "1 & 2" (1998).

Sailin' down the river
To New Orleans
To New Orleans
Bet my money by the gamblin' rules
Goin' from town
Town to town
Town to town
Come and lay your dollar down
Bound to lose
Bound to lose
Bound to lose
Riverboat gambler's bound to lose

Here comes Susie
With her hair piled high
With her hair piled high
Sister Sue keeps a-watchin' her eye
Hookers and hustlers
Follow her around
Follow her down
Come and lay your dollar down
Bound to lose
Bound to lose
Bound to lose
Riverboat gambler's bound to lose

Wheelin' an' a-dealin'
'Round she goes
Around she goes
Where she stops, nobody knows
Listen, good people
If you want the news
If you want the news
A riverboat gambler's bound to lose
Bound to lose
Bound to lose
Bound to lose
A riverboat gambler's bound to lose

Rouge on faces
Fancy clothes
Those fancy clothes
Money comes, and the money goes
Moon and stars
Sometimes I feel
Sometimes I feel
He's not, she's not, it's not real
It's not real
It's not real
It's not real
He's not, she's not, it's not real
Bound to lose
Bound to lose
Bound to lose
Riverboat gambler's bound to lose

[Very nearly the same lyrics are sung by:
Paul Geremia on "Hard Life Rockin' Chair" (2000),
Peter Tork & Shoe Suede Blues on "Cambria Hotel" (2007), and
Grandpa Banana on "Just Trying to Break Even" (2011),
and there are several other songs with the same title.]