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Mr. Caputo charged that scientists “deep in the bowels of the C.D.C.” walked “around like they are monks” and “holy men” but engaged in “rotten science.”

He fiercely defended his scientific adviser, Dr. Paul Alexander, who was heavily involved in the effort to reshape the C.D.C.’s Morbidity and Mortality Weekly Reports. Mr. Caputo described Dr. Alexander, an assistant professor at McMaster University in Canada, as “a genius.”

“To allow people to die so that you can replace the president is a grievous venial sin, venial sin,” Mr. Caputo said. “And these people are all going to hell. The shooting will begin if Biden does not concede”