I use Excel, Word (as a text editor under macros) and Notepad. If I can do it in HTML it will appear as intended on most browsers.
like my library who are paranoic about access and viruses, IE3 users, and who knows what browsers.
my website (cresby.com) doesn't look flash but is a purveyor of information not a showpiece for my skills with programs that do it all for you anyway.
Ask yourself what does your website do for you. AND what is it doing for the intended audience. The tools will suggest themselves after that.
I find a lot of technical sites assume you have loaded "Flash" and Javascript is running in IE5 and you can't get at the right pages without it.
My company's policies preclude some of these things.