You can run the program. I believe it just restores settings. If yours haven't changed it shouldn't do anything.

This worm is quite new, and McAfee may not be that current. The F-Secure site appears to have added info on this one only yesterday.

After you run the downloadable program, look for the virus here: c:\recycled\SirC32.exe and delete that file (src32.exe)
You can also use Windows Explorer/Tools/Find/Files or folders, and tell it to look for sirc32.exe, then delete it.

Also make sure you delete infected e-mail in in-boxes and out-boxes.

I'm not really an expert on this, and I'm just 'winging' it. If anyone who knows better wants to jump in...