A friend of mine does a guiness stew that is incredible.

Here's his recipe as he gave it to me:

a couple pounds of onions; slice thinly; cook in a little oil until just begin to brown; add cubed beef ( he said about three pounds) 2 bay leaves,1 teaspoon of paprika, 2 teaspoons cracked black pepper.

Add Guiness about 2/3 of the way up the meat. cover and cook on a slow simmer at least 4 hours. Salt to taste.