Modern wheat durum wheat has a far far higher percentage of gluten than the wheat of earlier centuries--it's a major change. And modern bread made by the fast factory Chorley Wood process is also very very different from the bread of a century ago. The high-speed rise and various additives mean that the wheat is far less broken down by fermentation than in traditional processes. If you are skeptical about non-coeliac gluten sensitivity, consider the interesting example of people who report that slow-fermented sourdough bread agrees with them much better than other types. In slow-fermented breads with wild yeast, the gluten has been much more broken down by the action of the yeast than in fast-process bread. The changes in wheat and bread due to modern production and selection are huge. The intestinal microbiome also varies hugely between individuals...
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