Very interesting Jack - I wasn't aware that epigenetic effects are caused by nicotine.

I've often wondered why there are so very many ADHD children nowadays. It would seem that a mother smoking can affect her baby's mental development, but this new research demonstrating that sperm can be affected (and down the generations into the bargain!) is astonishing.

I wonder if any other drugs (cocaine, amphetamines, heroin, ecstasy etc) produce similar impairment of offspring?

I'm so glad I have never smoked and neither did my parents.
And I hate passing people puffing away at the door of shops and supermarkets. Even 'vaping' stinks, especially if one doesn't smoke. My sense of smell is very acute!