Barbara Harris was married to Paul Sills who founded Second City. He is a stage director, taught at Yale and is the son of the mother of improvisation, Viola Spolin.

Barbara was turned off by Hollywood. Having lived in that town for too long I certainly understand why. Generally it takes great talent into its fold and renders it mediocre.
Look what happened to Richard Burton who was destined to become a classic actor but never achieved the stature of an Olivier or others from the Old Vic.

Or Dick Powell who had a beautiful tenor voice and was shoehorned into corny private detective Noir flix. Or great stories which were butchered by studio heads.

Barbara was great in the Second City and with her rival Elaine May.