What Murray and Rick said.
I have fairly large, wide, hands but with proportionally short fingers - I need a men's large in a glove, but the fingers are usually longer than I need - and I can no longer play a narrower neck than 1 3/4" at the nut, with any comfort.
Of course, that could be partly loss of flexibility in the hands with age. I played 1 11/16" necks for years with no real problem except finding a good way to finger a first-position A chord.
Peter.