Steve-o, Flaco Jiminez is one of the most exciting players I've ever heard live (I think Conwy Festival c. 1986/87) but surely the accordion is his first instrument???

In the folk world, I can't think of any that meet your criteria but I'd imagine there are a great number of people who can at least play one or more forms of the accordion to some degree - let's face facts, most of us have probably dabbled with another instrument at some time...