The Mudcat Café TM
Thread #62502   Message #1010613
Posted By: Mark Cohen
30-Aug-03 - 12:02 AM
Thread Name: BS: Procarin - MS treatment?
Subject: RE: BS: Procurin - MS treatment?
Well, as best I can tell, Procurin may be a trade name for a form of platelet-derived growth factor. That's a substance that is ubiquitous in the body, involved in the stimulation of growth of various connective tissue cells. There are some papers suggesting that it can be very helpful in healing pressure ulcers and other wounds that don't heal very well. There's also some in vitro (test tube) evidence that it stimulates growth of the supportive cells in the nervous system, which may be why somebody thought it might help in MS.

However. (1) It is a locally-active substance, meaning that if you rubbed it on your skin, it would not magically find its way to your brain. (2) Not surprisingly, PDGF has also been associated with tissue growth that is not so helpful, including fibrosis of the retina, arteriosclerosis, and some cancers. The specific PDGF receptors in a particular tissue determines how the tissue will respond to the substance. You can't pick and choose what you want it to do. (3) While you can extract PDGF from a sample of blood by allowing it to clot, it is generally made using recombinant DNA technology, inducing E. coli bacteria to make the stuff in large amounts. (4) It's not a "new drug" -- PDGF has been available commercially for years, used in laboratories that grow cells in tissue culture, mostly for research. And it's not even a drug at all.

Most likely, the MS patients who got better by rubbing Procurin on their skin would also have gotten better by rubbing plumeria massage oil on their skin...and they would have had lots more fun, and probably smelled nicer, too. And, as the folks above have pointed out, these "miracle" testimonials don't mention the follow-up reports, how many of the people who were "cured" went on to have yet another recurrence of their illness.

Obviously, I'm not telling people like Art and Mary anything they don't already know. And I'm not faulting Sinsull at all for posting--you never know which one of these things will wind up being the one that has some benefit. But I don't think it's this one.

(This will tell you more than you would ever want to know about PDGF.)

Aloha,
Mark