It isn't funny unless it's funny! But when it is funny, don't get dyslexics started on dyslexic jokes, because they know hundreds, and you'll get tired of them first.
As for telling blind jokes, I did once, having come into the club late, and received huge applause.
Then the compere told me there were 30+ totally blind people in the audience, a bus trip from a 'blind school' as they used to be called.
They thought I was taking the piss out of them, and they loved it.