the thing with a pickup line is that the lass in question (or the gent) KNOWS it is a pickup line, so it has to actually be a little cute... checking the tag on the back of her shirt to see if she was "Made in Heaven" doesn't cut it anymore... Though, one that I like and that I have gotten decent response from (as long as you say it with a little grin)...

"Where have you been all my nights, besides my dreams?"