There are lots of instruments where laterality does not even come up. Piano for example. Playing stringed instruments strung "backwards" is a definite disadvantage as far as I've seen. You have to always use your own instrument, it's difficult for right handed players to teach you, chord charts are set up for right-handers. My left handed husband says he had a positive advantage,as a beginer, being able to manage the fingering more quickly with his dominant hand. He says he reckons that stringed instruments are designed for left-handers and there would be more reason to string them "backwards " for right-handers. Joy