There are two levels of problem

1. People's own filters. They can turn them up high and zap anything where they are on bcc, often without seeing it. The only way around this is to send a welcome message to each new recipient reminding them to put your address in their "safe list".

2. ISPs own filtering. They can take a dislike to whole servers. If your ISP uses a backbone that has also been used by spammers you may loose a lot of messages.

You need to read every bounce message and determine what the underlying problem is. Also keep your address list clean, there is no point in sending to closed accounts time after time.