I have heard quite a few Puff parodies, including

Puff the Marijuana

Puff the Fucked Up Pot-Head

Fuck the Giant Penis

AIDS the Nasty Virus

Ralph the Magic Faggot
a/k/a Ralph the Magic Drag Queen

Pat the Irish Faggot
a favorite at the NYC St. Patrick's Day parade

Squish the Tiny Maggot

and most recently

Bush the Tragic Puppet.

I presume there are many more.