Limitation (of Self and of Life).

(often expressing as: cynicism, pessimism, disbelief, self-hatred, ignorance, hatred of others, rejection of life, withdrawal, depression, reductionism, negativism, and similar mental-emotional habits/philosophies...all springing from the original incorrect assumption of extreme limitation.)

If there is an original sin, that's it: The belief in limitation (and separation). Directly from it spring the other 7.