Since being rear-ended 4 yrs back, there are several injuries to include my brain being screwed up so that it is extremely difficult to learn a new tune, & damn near impossible to learn new lyrics. The loss of dexterity with all of the above is difficult to deal with. As Banjoman says, I keep playing despite all the crapola. If I didn't play I would lose my mind completely--& I need all my mind I can keep. I can't play for long periods of time. Since I play many instruments, I switch instruments frequently to keep my hands & body from being in the same position all the time. If I have to play one instrument for some time, then I sit & stand & pause & shake my hands & do whatever I have to do to get by. The quality of instrument you play in important, since cheaper instruments make us work harder. I have been looking for a smaller guitar which will fit my needs & make it easier on the arthritis, double carpal tunnel, nerve & muscle damage & such fun things. My hands get really cramped fast, & the muscles simply cease to function. An electric size neck makes it easier on my hands & wrists, though I vastly prefer acoustic.
    I encourage you to try different things to make it easier for you & keep on pickin' no matter what!