Important thing to remember about anti-spyware stuff is to stick to the free ones - AdAware and Spybot Search & Destroy for example. Some of the paid ones are untrustworthy (to be polite) and none do a better job. Get WinPatrol - with that you can find out what's running and what's in your startup. It's free, and you can use it to disable things that are in startup, and it gives more easily understandable info than Ctrl-Alt-Delete does.