List of 25 questions Science journal considers could be solved in the next 25 years:

- What is the universe made of?

- What is the biological basis of consciousness?

- Why do humans have so few genes?

- To what extent are genetic variation and personal health linked?

- Can the laws of physics be unified?

- How much can human life span be extended?

- What controls organ regeneration?

- How can a skin cell become a nerve cell?

- How does a single cell become a whole plant?

- How does earth's interior work?

- Are we alone in the universe?

- How and where did life on earth arise?

- What determines species diversity?

- What genetic changes made us uniquely human?

- How are memories stored and retrieved?

- How did cooperative behaviour evolve?

- How will big pictures emerge from a sea of biological information?

- How far can we push chemical self-assembly?

- What are the limits of conventional computing?

- Can we selectively shut off immune responses?

- Do deeper principles underlie quantum uncertainty and nonlocality?

- Is an effective HIV vaccine feasible?

- How hot will the greenhouse world be?

- What can replace cheap oil and when?

- How can a growing world population live sustainably on the planet?