I caught part of an interview with Neil young on NPR this morning. He was talking about his guitar "Hank" which once belonged to Hank Williams. He said something to the effect that some musicians would keep such a valuable and historically significant instrument under lock and key, but he just treats it like a normal guitar, playing it regularly, letting other people play it and, yes, taking it on the road. Instruments were meant to be played, not looked at.