We have all sorts of problems with some of the clients we deal with at work with Panda since Titanium (and Platinum) came out (we produce estate agency software and have several thousand users round the country). Truprevent seems to cause various problems like blocking parts of internet uploads - preventing text files being opened - reporting index problems in database files - to mention a few.

We don't have the same problems with other anti virus products but it's probably the 'intelligent'/heuristic part of the Truprevent thing that f***s things up which you don't want to be!