If it has anything to do with proteinuria and blood in the urine, be sure to ask about the correlation between sleep apnea and those conditions. My nephrologist told me they are finding use of a CPAP, at night, can help. I had both of those problems for years with no explanation of why...none of the tests came out positive for the usual suspects. The lack of enough oxygen due to sleep apnea seems to be the only explanation AND the only thing which has helped.