The source of the music does tend to dictate the style of the music. Sampling can definitely create new songs (vis PM Dawn, Vanilla Ice in the early 90s), but as Hyperabid says, the trick is to make the sampling part of the song, rather than basing a song round sampling. For example, Lloyd Webber all sounds a particular way bcos he writes on the piano, and that limits him to a particular range of expression when he's writing.

Sampling's just another musical tool. Didn't everyone forecast the death of real instruments when synths came out? And aren't there still plenty of musicians out there?

Grab.