I must try to persuade Ted Edwards to contribute to this thread... a stroke paralysed him down his right side in 1992, and took away his ability to speak.
He's managed to overcome many of the obstacles fate put in his way... he learned to walk again (with a stick) using his 'dead' leg by locking the knee - ingenious.
Speech was more of a problem, and is only partly restored. He can manage complete sentences or gibberish on an ad hoc basis...!
He doesn't think he'll ever play guitar again, though he keeps it on the off chance.