As a right handed person who learned guitar the usual way, I've always thought that the left hand had the more difficult role.

While lefties playing non-standard ("left-handed") instruments are at a disadvantage when trying to buy or borrow a guitar, they are at a distinct advantage when they don't want to lend their own instrument.

I have a very old friend, lefthanded, who became a luthier during the many years we didn't see each other. When we met again not long ago, he had made himself his own very nice lefthanded guitar, and tends to gloat about how he never lands it to anyone, and rarely has to explain or aplogize.