I like machine stitching and my granny taught me how to machine things properly - she was a stitcher in a factory all her life. She used to slap my wrist (not hard! She's a nice granny!) if I held the material the wrong way and would regale me with tales of how people sewed their fingers if they weren't paying attention.

I like hand-quilting but I'm a bit worried about RSI - I got tendonitis in my wrist last year from doing very repetetive mouse movements on a digital imaging project. That was not pleasant.