spools.exe is a component of a couple of virus/worm malware infections. The closest legitimate Windows files are spoolsv.exe and spoolse.dll.

The worms that include spools.exe are reported as attempting to disable common antivirus programs. A recommended procedure for worms of this kind, if they've gotten past your AV program, is that you go to one of the AV makers' sites and let the site do a remote scan of your computer. If the remote scan finds something that your installed AV didn't, you will need to get a clean copy (reinstall and update) of your own AV.

John