To clarify, in hand gesture #2 of "Talk To The Hand", the right hand palm of the person saying this is held at her neck level. Thus the person's face is looking in one direction {left} and the right hand is facing the opposite direction {right} toward the person being addressed. The hand is either held palm up very close to the person's neck level or the person saying "Talk to the hand"stretches her right arm out with her palm up.

The bottom line is that a person who says "Talk to the hand" is definitely not joking.