"...Blowing the US's entire inventory of high-level nuclear waste into the stratosphere..."

Not to worry, at least about a Nevada earthquake causing a huge radioactive event.

The great majority of waste from our nuclear reactors is neatly stored near them, all over the country. Convient places for terrorists to target. Little has been transported across the country as moving would be done on railways or on the Interstate Freeway System and would require several levels of governmental approval.