Walt Kelly was the creator of Pogo, a character and in a comic strip of the same name. IMO, Kelly was an adept and bright social commentator in the course of his cartooning career. He died about 30 years ago.

The strip I alluded to is linked to below. That particular page is framed by people on occasion. I don't know whether it's a 'famous' cartoon, but it was certainly well known years back.

Here.