As someone who lost his job and found a new and better one:

1. Don't limit yourself geographically. If you have to, move.

2. Network, network, network. That's what friends are for.

3. Get into a support group.

4. Follow up each interview with a thank-you note.

5. Receptionists and secretaries usually know more than the guy interviewing you. Talk with them if you can.

6. Never give up.