If you're going to Biltmore then a side trip to the Smokys is do-able, but there is a real traffic jam through there in the summer and it is hard on brakes. Lots of folks do the down side with smoking breaks. And if you should think about a visit to the Smokys, DON'T go near Gatlinburg. It's a crowded little tourist trap hell hole where everything is too cute for words, expensive as anything you'll find, and not worth the trouble. Clingman's Dome (at the top) is a modest little hike. But I'd head back down the Cherokee side again and stay out of Tennessee.

SRS